New product and new technology The working principle of the dryer is: the material is constantly turning in the double-cone rotary tank and exchanges heat with the tank wall. The outside of the tank wall is surrounded by a half pipe, and the half pipe is heated by circulating water with hot water. When the cone rotates, the crushing knife rotates at the same time. Whenever the tank rotates once, the material contacts with the crushing knife once. Since the speed of the crushing knife is faster, the maximum is 250 rpm, and the speed of the tank is slow, generally 3 rpm. Therefore, each When the material is in contact with the tool, the crushing effect is very obvious; the system in the tank is operated under vacuum conditions, taking into account the recovery of the organic solvent. Because the boiling point of the solvent is lower, the chilled water is used for condensation cooling to ensure that the solvent can be recycled and avoided. After being pumped away by the vacuum pump, it will pollute the atmosphere, so as to achieve the purpose of material crushing and drying.
The main basis and technical parameters of the design 2: Tank rotation speed: ~ 4rpm adjustable tank volume: 3000L hot water temperature: 1. Chilled water temperature: 5: (M) Material name: Antibiotic (15) Mechanical seal at the vacuum end The hot water end adopts rotary joints, the crushing knife device adopts magnetic fluid sealing, and the manhole cover is sealed with imported expanded PTFE gaskets; the rest is designed and manufactured with reference to the technical requirements of common double cones. 3. In the whole design and manufacture During the process, we always implement and strictly grasp the following two principle issues: 1 Equipment design and manufacturing must be strictly in accordance with the GMP (Good Manufacturing Practice); 2 The electrical equipment of the system must be strictly in accordance with the explosion-proof requirements, explosion-proof rating dAT4; Throughout the development process, we always adhere to the combination of design and production, equipment and process integration, installation and use of the principle of integration.
After more than one year's operation, Liaoning Meiya Pharmaceutical Co., Ltd. has a good working condition. The indicators such as drying strength, gas leakage rate, ultimate vacuum degree and hydraulic strength meet the standards and also meet the aseptic production process. Requirements, the dry materials, regardless of color, size, moisture content, yield and other technical and economic indicators are satisfactory, in full compliance with the requirements of the GMP.
The aircraft passed the scientific and technological achievements appraisal of Jiangsu Province in October 2003.
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